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Cosmedix Refine Plus

Cosmedix Refine Plus

Firm, Smooth and moisturize!

Cosmedix Refine 8% is a trans-retinol serum as potent as Retinoic Acid. It is chirally corrected to reduce irritation and photo sensitivity with increased effectiveness.

Improves skin’s texture,smoothness, and firmness. Essential for the generation and function of skin cells and collagen/elastin production. Helps dispersion of melanocytes bunching to break up stubborn hyper pigmentation.


Product Details


This powerful concentration of chirally corrected Vitamin A serum takes Refine Plus to the next level for enhanced results. Its collagen repair stimulating properties make it a potent anti-aging tool.


  • Increases cellular turnover Less irritation/redness than with other retinoids
  • Stimulates collagen/elastin/GAG production
  • Reduces fine lines/signs of aging Improves skin texture and color
  • Anti-acne/anti-bacterial/anti-sebum.
  • Helps to even skin tone by reducing the look of acne scars, dark spots and hyper-pigmentation
  • Free radical-fighting antioxidants defend skin from environmental stress that can cause inflammation and damage to collagen and elastin

How to use:

  • Apply a pea-sized amount to clean skin every other evening until tolerance allows for nightly use
  • Do NOT apply to eyelids
  • Discontinue use if redness or irritation occurs; resume at a lower dosage after discomfort has subsided
  • May experience mild peeling
  • Use caution when applying to neck and chest area


Aqua (Water), Hamamelis Virginiana (Witch Hazel) Water, Retinol, Cassia Angustifolia Seed Polysaccharide, Glycerin, Sodium Lactate, Proline (L), Sodium PCA, Sodium Hyaluronate (L), Squalane, Dimethicone Copolyol, Helianthus Annuus (Sunflower) Seed Oil, Galactoarabinan, Xanthan Gum, Benzyl Alcohol, D-glucuronic Acid, Santalum Album (Sandalwood) Oil, Jasminum Officinale (Jasminum) Extract, Citrus Aurantium Bergamia (Bergamot) Fruit Oi